High grade surface osteosarcoma

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Report of four cases with high-grade surface osteosarcoma.

High-grade surface osteosarcoma is the rarest of the three types of surface osteosarcoma. Four cases with high-grade surface osteosarcoma arising from the distal femur and tibia are reported in this study. One patient was previously diagnosed with Turner's syndrome. Radiologically, three cases presented characteristic appearances suggesting high-grade bone-forming sarcoma arising from the bone ...

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Improvement in High-Grade Osteosarcoma Survival

The aim of this study was to compare survival before and after 2004 and define the prognostic factors for high-grade osteosarcomas beyond those of typical young patients with localized extremity disease. Few studies have reported the long-term treatment outcomes of high-grade osteosarcoma in Taiwan. A total of 202 patients with primary high-grade osteosarcoma who received primary chemotherapy a...

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mTORC1 Maintains the Tumorigenicity of SSEA-4+ High-Grade Osteosarcoma

Inactivation of p53 and/or Rb pathways restrains osteoblasts from cell-cycle exit and terminal differentiation, which underpins osteosarcoma formation coupled with dedifferentiation. Recently, the level of p-S6K was shown to independently predict the prognosis for osteosarcomas, while the reason behind this is not understood. Here we show that in certain high-grade osteosarcomas, immature SSEA-...

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Allograft arthrodesis of the knee in high-grade osteosarcoma.

BACKGROUND A retrospective cohort study was conducted to evaluate the outcomes of massive allograft arthrodesis in the management of high-grade osteosarcoma around the knee. METHODS The results of 19 patients with high-grade osteosarcoma around the knee, which was treated by wide resection and reconstruction using allograft arthrodesis, were evaluated for a mean length of 7.3 years (range, 3-...

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High-grade intramedullary osteosarcoma of the talus: case report.

This is a presentation of a rare malignant tumor that uncommonly affects the bones of the foot. The following case involves a malignancy which usually presents during childhood or adolescence presenting much later in life. Physicians treating the foot and ankle must include osteosarcoma in their list of differential diagnoses to exclude when vague symptoms involving deep pain and edema present....

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ژورنال

عنوان ژورنال: Cancer

سال: 1999

ISSN: 0008-543X

DOI: 10.1002/(sici)1097-0142(19990301)85:5<1044::aid-cncr6>3.0.co;2-a